University of Sussex
Browse

File(s) not publicly available

Measuring impulsivity in mice: the five-choice serial reaction time task

journal contribution
posted on 2023-06-07, 18:37 authored by S Sanchez-Roige, Yolanda Pena-OliverYolanda Pena-Oliver, D N Stephens
RATIONALE Mice are useful tools for dissecting genetic and environmental factors in relation to the study of attention and impulsivity. The five-choice serial reaction time task (5CSRTT) paradigm has been well established in rats, but its transferability to mice is less well documented. OBJECTIVES This study aims to summarise the main results of the 5CSRTT in mice, with special focus on impulsivity. METHODS The 5CSRTT can be used to explore aspects of both attentional and inhibitory control mechanisms. RESULTS Different manipulations of the task parameters can lead to different results; adjusting the protocol as a function of the main variable of interest or the standardisation of the protocol to be applied to a large set of strains will be desirable. CONCLUSIONS The 5CSRTT has proven to be a useful tool to investigate impulsivity in mice.

History

Publication status

  • Published

Journal

Psychopharmacology

ISSN

1432-2072

Publisher

Springer Verlag

Issue

2

Volume

219

Page range

253-270

Department affiliated with

  • Psychology Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC