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Genealogies of mouse inbred strains

journal contribution
posted on 2023-06-07, 20:12 authored by J A Beck, S Lloyd, Majid HafezparastMajid Hafezparast, M Lennon-Piece, J T Eppig, M F Festing, E M Fisher
The mouse is a prime organism of choice for modelling human disease. Over 450 inbred strains of mice have been described, providing a wealth of different genotypes and phenotypes for genetic and other studies. As new strains are generated and others become extinct, it is useful to review periodically what strains are available and how they are related to each other, particularly in the light of available DNA polymorphism data from microsatellite and other markers. We describe the origins and relationships of inbred mouse strains, 90 years after the generation of the first inbred strain. Given the large collection of inbred strains available, and that published information on these strains is incomplete, we propose that all genealogical and genetic data on inbred strains be submitted to a common electronic database to ensure this valuable information resource is preserved and used efficiently.

History

Publication status

  • Published

Journal

Nature Genetics

ISSN

1061-4036

Issue

1

Volume

24

Page range

23-25

Department affiliated with

  • Neuroscience Publications

Full text available

  • No

Peer reviewed?

  • No

Legacy Posted Date

2012-02-06

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