File(s) not publicly available
Yeast vacuoles: more than a model lysosome
journal contribution
posted on 2023-06-07, 21:50 authored by John ArmstrongThanks to their amenability to both genetic and biochemical analysis, vacuoles of S. cerevisiae are valuable models for trafficking processes to mammalian lysosomes. They also have additional functions to lysosomes, and all of these processes can influence the size and number of vacuoles. Several recent papers have indicated that some vacuolar proteins participate in more than one process, and hence could be regulatory points to balance the processes and control vacuole dimensions. Studies of vacuoles from other yeasts and fungi are uncovering further roles for vacuoles, increasing the apparent requirement for such regulation. Having served as models in the past, yeast vacuoles are now well suited to develop the next generation of quantitative methods to understand organelle functions and dynamics.
History
Publication status
- Published
Journal
Trends in Cell BiologyISSN
0962-8924Publisher
ElsevierExternal DOI
Issue
10Volume
20Page range
580-585Department affiliated with
- Biochemistry Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC