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Cell signaling: The BRCT domain: signaling with friends?

journal contribution
posted on 2023-06-08, 09:58 authored by Keith CaldecottKeith Caldecott
The tandem BRCT domains of the tumor suppressor protein BRCA1 are thought to contribute to this protein's function in the cellular response to DNA damage. In his Perspective, Caldecott discusses new work ( Yu et al., Manke et al.) showing that the BRCT domains of BRCA1 and of other proteins bind specifically to phosphorylated amino acids in their protein partners.

History

Publication status

  • Published

Journal

Science

ISSN

0036-8075

Publisher

American Association for the Advancement of Science

Issue

5645

Volume

302

Page range

579-580

Department affiliated with

  • Sussex Centre for Genome Damage Stability Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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