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Fluorescence of commercial Pluronic F127 samples: Temperature-dependent micellization

journal contribution
posted on 2023-06-08, 12:30 authored by Christopher C Perry, Theodore S Sabir, Wesley J Livingston, Jamie R Milligan, Qiao ChenQiao Chen, Victoria Maskiewicz, Danilo S Boskovic
We present a novel approach of using the butylated hydroxytoluene (BHT) antioxidant found in commercial Pluronic F127 samples as a marker of polymer aggregation. The BHT marker was compared to the pyrene dye and static light scattering methods as a way to measure the critical micelle concentration (CMC) and critical micelle temperature (CMT). The n?p(*) transitions of BHT are sensitive to the microenvironment as demonstrated by plotting the fractional intensities of its excitation (˜280nm) and emission (˜325nm) peaks. BHT is more sensitive to changes in temperature than concentration. The partition coefficient increases ˜40-fold for pyrene compared to ˜2-fold for BHT when the temperature is increased from 25 to 37°C. CMT values determined using the BHT fluorescence decrease with increasing F127 concentration. Our results show that BHT can be used as a reliable marker of changes in the microenvironment of Pluronic F127.

History

Publication status

  • Published

Journal

Journal of colloid and interface science

ISSN

1095-7103

Publisher

Elsevier

Issue

2

Volume

354

Page range

662-669

Department affiliated with

  • Chemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-10-29

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