WO2012-080721patent.pdf (1.73 MB)
Novel biomarkers in plasma cell disorders
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posted on 2023-06-08, 13:35 authored by Sarah NewburySarah Newbury, Timothy ChevassutTimothy Chevassut, Chris JonesChris Jones, Maria Vadilyevna Zabolotskaya, Helen StewartThe invention relates to novel biomarkers for plasma cell disorders, such as multiple myeloma,and in particular the use of microRNAs as diagnostic and prognostic markers in assyas for detecting such disorders. The invention also relates to methods of determining the efficacy of treating such a plasma cell disorder with a therapeutic agent and kits for carrying out the assays and methods. The assays are qualitative and/or quantitative and are adaptable to large-scale screening and clinical trials.
Funding
Drug-induced selective lethality in populations of DNMT3A knockdown cells; G2782; WELLCOME TRUST; 218435/Z/19/Z
In vitro modelling and therapeutic targeting of tumour cell migration in chronic lymphocytic leukaemia.; G2544; BLOODWISE; 18005
How does SARS CoV-2 infect blood vessels?; G3146; UK RESEARCH AND INNOVATION; MR/V036750/1
Modelling and targeting Acute Myeloid Leukaemia cells in the Bone Marrow protective niche; G3106; SUSSEX CANCER FUND FOR TREATMENT AND RESEARCH
Mining the Wnt signalling-responsive surfaceome for drug targets in acute myeloid leukaemia; G3090; WELLCOME TRUST
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- Published
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- Clinical and Experimental Medicine Publications
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2012-11-09Usage metrics
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