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Molecular diagnosis of Fusobacterium necrophorum infection (Lemierre's syndrome)
journal contribution
posted on 2023-06-08, 17:09 authored by S H Aliyu, P F K Yong, Melanie NewportMelanie Newport, H Zhang, R K Marriott, M D Curran, H LudlamPresented here is the case of a 27-year-old male with atypical features of Lemierre's syndrome in which a definitive diagnosis was achieved using molecular methods. While routine investigations, including bacterial cultures, were unhelpful, two real-time PCR assays demonstrated Fusobacterium necrophorum-specific DNA in aspirates from brain and renal abscesses. This is the first report demonstrating that a laboratory diagnosis can be made using molecular methods in suspected cases of Lemierre's syndrome. Use of these methods can thus resolve diagnostic confusion, prevent unnecessary investigation, and direct specific antimicrobial treatment.
History
Publication status
- Published
Journal
European Journal of Clinical Microbiology and Infectious DiseasesISSN
0934-9723Publisher
Springer VerlagExternal DOI
Issue
3Volume
24Page range
226-229Department affiliated with
- Primary Care and Public Health Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2014-05-09Usage metrics
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