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The association between conduct problems and the initiation and progression of marijuana use during adolescence: a genetic analysis across time

journal contribution
posted on 2023-06-08, 21:45 authored by Katherine Shelton, Kate Lifford, Tom Fowler, Frances Rice, Mike Neale, Gordon Harold, Anita Thapar, Marianne van den Bree
The present study used a prospective, longitudinal design to investigate genetic and environmental influences on the association between earlier conduct problems and the initiation and progression of marijuana use during adolescence. Parent- and teacher-reported conduct problems assessed at Time 1 (1996) and self-reported marijuana use assessed at Time 2 (2004) were available for 1088 adolescent twin pairs participating in the Cardiff Study of All Wales and North West of England Twins (CaStANET). Using a novel approach to the modeling of initiation and progression dimensions in substance use, findings suggested that the initiation of marijuana use in adolescence was influenced by genetic, common and unique environmental factors. The progression (or frequency) of marijuana use was influenced by genetic and unique environmental factors. Findings for conduct problems indicated that while the presence or absence of conduct problems was largely heritable, the relative severity of conduct problems appeared to be more strongly environmentally influenced. Multivariate model fitting indicated that conduct problems in childhood and early adolescence made a small but significant contribution to the risk for marijuana use 8 years later. © 2006 Springer Science+Business Media, LLC.

History

Publication status

  • Published

Journal

Behavior Genetics

ISSN

0001-8244

Publisher

Springer New York

Issue

2

Volume

37

Page range

314-325

Department affiliated with

  • Psychology Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-08-11

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