http://sro.sussex.ac.uk/ http://sro.sussex.ac.uk/images/sitelogo.png http://sro.sussex.ac.uk/ Sun, 26 Nov 2023 04:13:14 +0000 Sun, 26 Nov 2023 04:13:14 +0000 en Fri, 19 May 2023 10:48:41 +0100 http://sro.sussex.ac.uk/id/eprint/112421/ http://sro.sussex.ac.uk/id/eprint/112421/ Bonnar, Orla, Shaw, Kira, Anderle, Silvia, Grijseels, Dori M, Clarke, Devin, Bell, Laura, King, Sarah and Hall, Catherine (2023) APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice. Journal of Cerebral Blood Flow and Metabolism. ISSN 0271-678X (Accepted) Tue, 14 Jun 2022 16:49:11 +0100 http://sro.sussex.ac.uk/id/eprint/106386/ http://sro.sussex.ac.uk/id/eprint/106386/ Steele, Oliver George, Stuart, Alexander Cameron, Minkley, Lucy, Shaw, Kira, Bonnar, Orla, Anderle, Silvia, Penn, Andrew Charles, Rusted, Jennifer, Serpell, Louise, Hall, Catherine and King, Sarah (2022) A multi-hit hypothesis for an APOE4-dependent pathophysiological state. Eur J Neurosci. ISSN 0953-816X Wed, 29 Jan 2020 08:15:26 +0000 http://sro.sussex.ac.uk/id/eprint/89636/ http://sro.sussex.ac.uk/id/eprint/89636/ Evans, Simon L, Dowell, Nicholas G, Prowse, Fenella, Tabet, Naji, King, Sarah L and Rusted, Jennifer M (2020) Mid age APOE ε4 carriers show memory-related functional differences and disrupted structure-function relationships in hippocampal regions. Scientific Reports, 10. a3110. ISSN 2045-2322 Fri, 01 Feb 2019 10:47:49 +0000 http://sro.sussex.ac.uk/id/eprint/81593/ http://sro.sussex.ac.uk/id/eprint/81593/ Dixon, Claire I, Walker, Sophie E, Swinny, Jerome, Belelli, Delia, Lambert, Jeremy L, King, Sarah and Stephens, David N (2019) Early life stress influences acute and sensitised responses of adult mice to cocaine by interacting with GABAA α2 receptor expression. Behavioural Pharmacology, 30 (2-3). pp. 272-281. ISSN 0955-8810 Fri, 19 Oct 2018 13:57:38 +0100 http://sro.sussex.ac.uk/id/eprint/79594/ http://sro.sussex.ac.uk/id/eprint/79594/ Mitchell, Scott J, Maguire, Edward P, Cunningham, Linda, Gunn, Benjamin G, Linke, Matthias, Zechner, Ulrich, Dixon, Claire I, King, Sarah L, Stephens, David N, Swinny, Jerome D, Belelli, Delia and Lambert, Jeremy J (2018) Early-life adversity selectively impairs α2-GABAA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine. Neuropharmacology, 141. pp. 98-112. ISSN 0028-3908 Mon, 02 Jul 2018 09:08:48 +0100 http://sro.sussex.ac.uk/id/eprint/76803/ http://sro.sussex.ac.uk/id/eprint/76803/ Evans, Simon, Clarke, Devin, Dowell, Nicholas, Tabet, Naji, King - Psychology, Sarah, Hutton, Samuel and Rusted, Jennifer (2018) Using event-related fMRI to examine sustained attention processes and effects of APOE ε4 in young adults. PLoS ONE, 13 (6). e0198312 1-18. ISSN 1932-6203 Mon, 27 Mar 2017 14:47:22 +0100 http://sro.sussex.ac.uk/id/eprint/67170/ http://sro.sussex.ac.uk/id/eprint/67170/ Duka, Theodora, Nikolaou, Kyriaki, King, Sarah L, Banaschewski, Tobias, Bokde, Arun L W, Büchel, Christian, Carvalho, Fabiana M, Conrod, Patricia J, Flor, Herta, Gallinat, Jürgen, Garavan, Hugh, Heinz, Andreas, Jia, Tianye, Gowland, Penny, Martinot, Jean-Luc, Paus, Tomáš, Rietschel, Marcella, Robbins, Trevor W, Schumann, Gunter, Smolka, Michael and Stephens, David N (2017) GABRB1 single nucleotide polymorphism associated with altered brain responses (but not 1 performance) during measures of impulsivity and reward sensitivity in human adolescents. Frontiers in Neuroscience, 11. a24. ISSN 1662-4548 Wed, 31 Aug 2016 13:54:05 +0100 http://sro.sussex.ac.uk/id/eprint/63064/ http://sro.sussex.ac.uk/id/eprint/63064/ Stephens, D N, King, S L, Lambert, J J, Belelli, D and Duka, T (2017) GABAA receptor subtype involvement in addictive behaviour. Genes, Brain and Behavior, 16 (1). pp. 149-184. ISSN 1601-1848 Fri, 04 Mar 2016 10:34:54 +0000 http://sro.sussex.ac.uk/id/eprint/59840/ http://sro.sussex.ac.uk/id/eprint/59840/ Dowell, Nicholas G, Evans, Simon L, Tofts, Paul S, King, Sarah L, Tabet, Naji and Rusted, Jennifer M (2016) Structural and resting-state MRI detects regional brain differences in young and mid-age healthy APOE-e4 carriers compared with non-APOE-e4 carriers. NMR in Biomedicine, 29 (5). pp. 614-624. ISSN 0952-3480 Wed, 17 Feb 2016 13:25:52 +0000 http://sro.sussex.ac.uk/id/eprint/59674/ http://sro.sussex.ac.uk/id/eprint/59674/ Duka, Theodora, Dixon, Claire I, Trick, Leanne, Crombag, Hans S, King, Sarah L and Stephens, David N (2015) Motivational effects of methylphenidate are associated with GABRA2 variants conferring addiction risk. Frontiers in Behavioral Neuroscience, 9. a304. ISSN 1662-5153 Tue, 15 Sep 2015 13:54:30 +0100 http://sro.sussex.ac.uk/id/eprint/56358/ http://sro.sussex.ac.uk/id/eprint/56358/ Evans, Simon, Dowell, Nicholas G, Tabet, Naji, Tofts, Paul Stephen, King, Sarah L and Rusted, Jennifer M (2014) Cognitive and neural signatures of the APOE E4 allele in mid-aged adults. Neurobiology of Aging, 35 (7). pp. 1615-23. ISSN 0197-4580 Tue, 15 Sep 2015 13:45:57 +0100 http://sro.sussex.ac.uk/id/eprint/56359/ http://sro.sussex.ac.uk/id/eprint/56359/ Evans, Simon, Dowell, Nicholas G, Tabet, Naji, Tofts, Paul S, King, Sarah L, Gray, Marcus and Rusted, Jennifer M (2013) Nicotine effects on attentional reorienting in mid-age adults, and interactions with apolipoprotein E status. Journal of Psychopharmacology, 27 (11). pp. 1007-14. ISSN 0269-8811 Wed, 29 Jul 2015 10:48:32 +0100 http://sro.sussex.ac.uk/id/eprint/55814/ http://sro.sussex.ac.uk/id/eprint/55814/ Caldarone, Barbara J, Zachariou, Venetia and King, Sarah L (2015) Rodent models of treatment-resistant depression. European Journal of Pharmacology, 753. pp. 51-65. ISSN 0014-2999 Wed, 02 Jul 2014 11:36:39 +0100 http://sro.sussex.ac.uk/id/eprint/49178/ http://sro.sussex.ac.uk/id/eprint/49178/ Dixon, C I, Halbout, B, King, S L and Stephens, D N (2014) Deletion of the GABAA α2-subunit does not alter self dministration of cocaine or reinstatement of cocaine seeking. Psychopharmacology, 231 (13). pp. 2695-2703. ISSN 0033-3158 Tue, 11 Mar 2014 16:46:53 +0000 http://sro.sussex.ac.uk/id/eprint/47816/ http://sro.sussex.ac.uk/id/eprint/47816/ Maguire, E P, MacPherson, T, Swinny, J D, Dixon, C I, Herd, M B, Belelli, D, Stephens, D N, King, S L and Lambert, J J (2014) Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants. Journal of Neuroscience, 34 (3). pp. 823-838. ISSN 0270-6474 Tue, 03 Sep 2013 11:58:12 +0100 http://sro.sussex.ac.uk/id/eprint/45994/ http://sro.sussex.ac.uk/id/eprint/45994/ Park, Aesoon, O'Malley, Stephanie S, King, Sarah L and Picciotto, Marina R (2014) Mediating role of stress reactivity in the effects of prenatal tobacco exposure on childhood mental health outcomes. Nicotine & Tobacco Research, 16 (2). pp. 174-185. ISSN 1462-2203 Fri, 19 Apr 2013 08:01:48 +0100 http://sro.sussex.ac.uk/id/eprint/44396/ http://sro.sussex.ac.uk/id/eprint/44396/ Stephens, Dai and King, Sarah L (2013) Neuropharmacology of benzodiazepines. In: Miller, Peter (ed.) Biological research on addiction: comprehensive addictive behaviors and disorders. Academic Press, San Diego, pp. 605-614. ISBN 9780123983350 Mon, 18 Mar 2013 13:13:19 +0000 http://sro.sussex.ac.uk/id/eprint/43739/ http://sro.sussex.ac.uk/id/eprint/43739/ Dowell, Nicholas G, Ruest, Torsten, Evans, Simon L, King, Sarah L, Tabet, Naji, Tofts, Paul S and Rusted, Jennifer M (2013) MRI of carriers of the apolipoprotein E e4 allele-evidence for structural differences in normal-appearing brain tissue in e4+ relative to e4- young adults. NMR in Biomedicine, 26 (6). pp. 674-682. ISSN 0952-3480 Fri, 15 Mar 2013 11:58:17 +0000 http://sro.sussex.ac.uk/id/eprint/42439/ http://sro.sussex.ac.uk/id/eprint/42439/ Evans, Simon, Gray, Marcus A, Dowell, Nicholas, Tabet, Naji, Tofts, Paul S, King, Sarah and Rusted, Jennifer M (2012) APOE E4 carriers show prospective memory enhancement under nicotine, and evidence for specialisation within medial BA10. Neuropsychopharmacology, 38 (4). pp. 655-663. ISSN 0893-133X Mon, 12 Nov 2012 09:41:55 +0000 http://sro.sussex.ac.uk/id/eprint/42001/ http://sro.sussex.ac.uk/id/eprint/42001/ Marchant, Natalie L, King, Sarah L, Tabet, Naji and Rusted, Jennifer M (2010) Positive effects of cholinergic stimulation favor young APOE epsilon4 carriers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35 (5). pp. 1090-6. ISSN 1740-634X Thu, 08 Nov 2012 12:32:23 +0000 http://sro.sussex.ac.uk/id/eprint/42365/ http://sro.sussex.ac.uk/id/eprint/42365/ Rusted, J M, Evans, S L, King, S L, Dowell, N G, Tabet, N and Tofts, P S (2013) APOE e4 polymorphism in young adults is associated with improved attention and indexed by distinct neural signatures. NeuroImage, 65 (1). pp. 364-373. ISSN 1053-8119 Mon, 28 May 2012 08:33:18 +0100 http://sro.sussex.ac.uk/id/eprint/39441/ http://sro.sussex.ac.uk/id/eprint/39441/ Terzi, Dimitra, Stergiou, Eugenia, King, Sarah L and Zachariou, Venetia (2009) Chapter 10: Regulators of G Protein Signaling in Neuropsychiatric Disorders. In: Fisher, Rory A (ed.) Molecular Biology of RGS Proteins. Progress in Molecular Biology and Translational Science, 86 . Elsevier Science, London, pp. 299-333. ISBN 9780123747594 Mon, 28 May 2012 08:27:10 +0100 http://sro.sussex.ac.uk/id/eprint/39440/ http://sro.sussex.ac.uk/id/eprint/39440/ King, Sarah L (2010) Mouse Genetic Approaches to Psychiatric Disorders. In: Koob, George F, Le Moal, Michel and Thompson, Richard F (eds.) Encyclopedia of Behavioral Neuroscience. Elsevier Science, London, pp. 280-285. ISBN 9780080453965 Mon, 28 May 2012 08:01:56 +0100 http://sro.sussex.ac.uk/id/eprint/39439/ http://sro.sussex.ac.uk/id/eprint/39439/ Peña-Oliver, Y, Buchman, V L, Dalley, J W, Robbins, T W, Schumann, G, Ripley, Tamzin, King, S L and Stephens, D N (2012) Deletion of alpha-synuclein decreases impulsivity in mice. Genes, Brain and Behavior, 11 (2). pp. 137-146. ISSN 1601-1848 Mon, 06 Feb 2012 15:51:44 +0000 http://sro.sussex.ac.uk/id/eprint/14776/ http://sro.sussex.ac.uk/id/eprint/14776/ King, Sarah L, Marks, Michael J, Grady, Sharon R, Caldarone, Barbara J, Koren, Andrei O, Mukhin, Alexey G, Collins, Allan C and Picciotto, Marina R (2003) Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. Journal of Neuroscience, 23 (9). pp. 3837-3843. ISSN 0270-6474 Mon, 06 Feb 2012 15:50:18 +0000 http://sro.sussex.ac.uk/id/eprint/14654/ http://sro.sussex.ac.uk/id/eprint/14654/ Stephens, D N, Belelli, D, Lambert, J J, Thomas, H and King, S L (2009) Gaba(A) receptor subunits: their contribution to ethanol and other addictive behaviours in mice. In: 32nd Annual Scientific Meeting of the Research Society on Alcoholism, 20-24th June 2009, San Diego, California. Mon, 06 Feb 2012 15:48:29 +0000 http://sro.sussex.ac.uk/id/eprint/14498/ http://sro.sussex.ac.uk/id/eprint/14498/ Mineur, Y S, Brunzell, D H, Grady, S R, Lindstrom, J M, McIntosh, J M, Marks, M J, King, S L and Picciotto, M R (2009) Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning. Genes, Brain and Behavior, 8 (3). pp. 257-266. ISSN 1601-1848 Mon, 06 Feb 2012 15:47:31 +0000 http://sro.sussex.ac.uk/id/eprint/14420/ http://sro.sussex.ac.uk/id/eprint/14420/ King, Sarah L, Caldarone, Barbara J and Picciotto, Marina R (2004) β2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration. Neuropharmacology, 47 (S1). pp. 132-139. ISSN 0028-3908 Mon, 06 Feb 2012 15:47:02 +0000 http://sro.sussex.ac.uk/id/eprint/14377/ http://sro.sussex.ac.uk/id/eprint/14377/ Picciotto, Marina R, Caldarone, Barbara J, Brunzell, Darlene H, Zachariou, Venetia, Stevens, Tanya R and King, Sarah L (2001) Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Pharmacology and Therapeutics, 92 (2-3). pp. 89-108. ISSN 0163-7258 Mon, 06 Feb 2012 15:44:58 +0000 http://sro.sussex.ac.uk/id/eprint/14202/ http://sro.sussex.ac.uk/id/eprint/14202/ Picciotto, Marina R, Caldarone, Barbara J, King, Sarah L and Zachariou, Venetia (2000) Nicotinic Receptors in the Brain: Links between Molecular Biology and Behavior. Neuropsychopharmacology, 22 (5). pp. 451-465. ISSN 0893-133X Mon, 06 Feb 2012 15:44:31 +0000 http://sro.sussex.ac.uk/id/eprint/14181/ http://sro.sussex.ac.uk/id/eprint/14181/ Dixon, Claire I, Morris, Hannah V, Breen, Gerome, Desrivieres, Sylvane, Jugurnauth, Sarah, Steiner, Rebecca C, Vallada, Homero, Guindalini, Camila, Laranjeira, Ronaldo, Messas, Guilherme, Rosahl, Thomas W, Atack, John R, Peden, Dianne R, Belelli, Delia, Lambert, Jeremy J, King, Sarah L, Schumann, Gunter and Stephens, David N (2010) Cocaine effects on mouse incentive-learning and human addiction are linked to α2 subunit-containing GABAA receptors. Proceedings of the National Academy of Sciences, 107 (5). pp. 2289-2294. ISSN 0027-8424 Mon, 06 Feb 2012 15:43:22 +0000 http://sro.sussex.ac.uk/id/eprint/14089/ http://sro.sussex.ac.uk/id/eprint/14089/ Harrist, Alexia, Beech, Robert D, King, Sarah L, Zanardi, Alessio, Cleary, Muriel A, Caldarone, Barbara J, Eisch, Amelia, Zoli, Michele and Picciotto, Marina R (2004) Alteration of hippocampal cell proliferation in mice lacking the beta(2) subunit of the neuronal nicotinic acetylcholine receptor. Synapse, 54 (4). pp. 200-206. ISSN 0887-4476 Mon, 06 Feb 2012 15:41:52 +0000 http://sro.sussex.ac.uk/id/eprint/13955/ http://sro.sussex.ac.uk/id/eprint/13955/ Caldarone, Barbara J, King, Sarah L and Picciotto, Marina R (2008) Sex differences in anxiety-like behaviour and locomotor activity following chronic nicotine exposure in mice. Neuroscience Letters, 439 (2). pp. 187-191. ISSN 0304-3940 Mon, 06 Feb 2012 15:39:41 +0000 http://sro.sussex.ac.uk/id/eprint/13773/ http://sro.sussex.ac.uk/id/eprint/13773/ Miwa, Julie M, Stevens, Tanya R, King, Sarah, Caldarone, Barbara J, Ibanez-Tallon, Ines, Xiao, Cheng, Fitzsimonds, Reiko Maki, Pavlides, Constantine, Lester, Henry A, Picciotto, Marina R and Heintz, Nathaniel (2006) The Prototoxin lynx1 Acts on Nicotinic Acetylcholine Receptors to Balance Neuronal Activity and Survival In Vivo. Neuron, 51 (5). pp. 587-600. ISSN 0028-3878 Mon, 06 Feb 2012 15:39:09 +0000 http://sro.sussex.ac.uk/id/eprint/13728/ http://sro.sussex.ac.uk/id/eprint/13728/ Heath, Christopher J, King, Sarah L, Gotti, Cecilia, Marks, Michael J and Picciotto, Marina R (2010) Cortico-thalamic connectivity is vulnerable to nicotine exposure during early postnatal development through α4/β2/α5 nicotinic acetylcholine receptors. Neuropsychopharmacology, 35 (12). pp. 2324-2338. ISSN 0893-133X Mon, 06 Feb 2012 15:39:00 +0000 http://sro.sussex.ac.uk/id/eprint/13715/ http://sro.sussex.ac.uk/id/eprint/13715/ Xu, Hong-Ping, Furman, Moran, Mineur, Yann S, Chen, Hui, King, Sarah L, Zenisek, David, Zhou, Z Jimmy, Butts, Daniel A, Tian, Ning, Picciotto, Marina R and Crair, Michael C (2011) An instructive role for patterned spontaneous retinal activity in mouse visual map development. Neuron, 70 (6). pp. 1115-1127. ISSN 0896-6273 Mon, 06 Feb 2012 15:38:16 +0000 http://sro.sussex.ac.uk/id/eprint/13650/ http://sro.sussex.ac.uk/id/eprint/13650/ Caldarone, B J, Karthigeyan, K, Harrist, A, Hunsberger, J G, Wittmack, E, King, S L, Jatlow, P and Picciotto, M R (2003) Sex differences in response to oral amitriptyline in three animal models of depression in C57BL/6J mice. Psychopharmacology, 170 (1). pp. 94-101. ISSN 0033-3158 Mon, 06 Feb 2012 15:37:50 +0000 http://sro.sussex.ac.uk/id/eprint/13610/ http://sro.sussex.ac.uk/id/eprint/13610/ Caldarone, Barbara J, Harrist, Alexia, Cleary, Muriel A, Beech, Robert D, King, Sarah L and Picciotto, Marina R (2004) High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. Biological Psychiatry, 56 (9). pp. 657-664. ISSN 0006-3223 Mon, 06 Feb 2012 15:31:31 +0000 http://sro.sussex.ac.uk/id/eprint/13073/ http://sro.sussex.ac.uk/id/eprint/13073/ Mukhin, Alexey G, Gündisch, Daniela, Horti, Andrew G, Koren, Andrei O, Tamagnan, Gilles, Kimes, Alane S, Chambers, Joann, Vaupel, D Bruce, King, Sarah L, Picciotto, Marina R, Innis, Robert B and London, Edythe D (2000) 5-Iodo-A-85380, an α4β2 Subtype-Selective Ligand for Nicotinic Acetylcholine Receptors. Molecular Pharmacology, 57 (3). pp. 642-649. ISSN 0026-895X Mon, 06 Feb 2012 15:30:57 +0000 http://sro.sussex.ac.uk/id/eprint/13024/ http://sro.sussex.ac.uk/id/eprint/13024/ Marchant, Natalie L, King, Sarah L, Tabet, Naji and Rusted, Jennifer M (2010) Positive Effects of Cholinergic Stimulation Favor Young APOE ε4 Carriers. Neuropsychopharmacology, 35 (5). pp. 1090-1096. ISSN 0893-133X