DNA single-strand break repair and spinocerebellar ataxia

Caldecott, K. W. (2003) DNA single-strand break repair and spinocerebellar ataxia. Cell, 112 (1). 7-10.. ISSN 0092-8674

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DNA single-strand break repair (SSBR) is critical for the survival and genetic stability of mammalian cells. Three papers have recently associated mutations in putative human SSBR genes with hereditary spinocerebellar ataxia. The emerging links between SSBR and neurodegenerative disorders are discussed.

Item Type: Article
Additional Information: GDSC52
Schools and Departments: School of Life Sciences
Depositing User: Gee Wheatley
Date Deposited: 26 Mar 2007
Last Modified: 30 Nov 2012 16:51
URI: http://srodev.sussex.ac.uk/id/eprint/1031
Google Scholar:96 Citations
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