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How do Rab proteins function in membrane traffic?

journal contribution
posted on 2023-06-07, 21:00 authored by John Armstrong
The Rabs are a group of GTP-binding proteins implicated for some time in the targeting of different transport vesicles within the cell, but it has been unclear how they function, or how they relate to a second group of targeting proteins, the SNAREs. Recent work, discussed in this review, has used biophysical, biochemical and genetic approaches to begin to answer these questions for Rab3, Rab5 and the yeast protein Sec4p. However, the results from these three Rabs lead to a surprising conclusion: the different Rabs seem to function via highly diverse target proteins

History

Publication status

  • Published

Journal

International Journal of Biochemistry and Cell Biology

ISSN

1357-2725

Publisher

Elsevier

Issue

3

Volume

32

Page range

303-307

Department affiliated with

  • Biochemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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