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Using worms to better understand how Bacillus thuringiensis kills insects

journal contribution
posted on 2023-06-07, 21:25 authored by Neil CrickmoreNeil Crickmore
Bacillus thuringiensis is widely used as a biological pesticide to control insects that either cause damage to crops or transmit disease. That it can also target the model organism Caenorhabditis elegans has not only provided exciting new insights into how the toxins produced by the bacterium target their victims but also how target insects counter the attack. Modern approaches such as reverse genetics and microarray technology have revealed novel receptors for the toxins and possible signal transduction pathways induced within the host following intoxication. This article will discuss how these findings fit in with current models and how they might influence future studies.

History

Publication status

  • Published

Journal

Trends in Microbiology

ISSN

0966-842X

Publisher

Elsevier

Issue

8

Volume

13

Page range

347-350

Pages

14.0

Department affiliated with

  • Biochemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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