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The peak to mean pressure decrease ratio: a new method of assessing aortic stenosis

journal contribution
posted on 2023-06-07, 14:53 authored by John Chambers, Ronak Rajani, Matthew Hankins, Robert Cook
Background: The ratio of peak to mean pressure decrease is a new measure of transaortic continuous waveform shape that could be useful for grading aortic stenosis. Methods: We retrospectively analyzed echocardiograms in 163 patients with all grades of aortic stenosis as assessed by the continuity equation. Results: The peak to mean pressure decrease ratio was 1.75 (0.14) in mild stenosis, 1.66 (0.13) in moderate stenosis, 1.56 (0.10) in severe stenosis, and 1.57 (0.07) in severe aortic stenosis with left ventricular ejection fraction less than 40%. Receiver operating characteristic curve analysis showed that a threshold of less than 1.50 gave a specificity of 94% against continuity area whereas a ratio less than 1.75 gave a sensitivity of 96%. Conclusion:The peak to mean pressure decrease ratio is a simple and quick cue to the likelihood of severe aortic stenosis in patients with low left ventricular ejection fraction when transaortic pressure decreases appear only moderate.

History

Publication status

  • Published

Journal

Journal of the American Society of Echocardiography

ISSN

0894-7317

Publisher

Elsevier

Issue

6

Volume

18

Page range

674-678

Department affiliated with

  • Primary Care and Public Health Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2008-10-24

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