DNA repair in the fission yeast, Schizosaccharomyces pombe

Lehmann, A R, Carr, A M, Watts, F Z and Murray, J M (1991) DNA repair in the fission yeast, Schizosaccharomyces pombe. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 250 (1-2). pp. 205-210. ISSN 0027-5107

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Mutants of the fission yeast Schizosaccharomyces pombe which are sensitive to UV and/or ¿-irradiation have been assigned to 23 complementation groups, which can be assigned to three phenotypic groups. We have cloned genes which correct the deficiency in mutants corresponding to 12 of the complementation groups. Three genes in the excision-repair pathway have a high degree of sequence conservation with excision-repair genes from the evolutionarily distant budding yeast Saccharomyces cerevisiae. In contrast, those genes in the recombination repair pathway which have been characterised so far, show little homology with any previously characterised genes.

Item Type: Article
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Depositing User: Alan Lehmann
Date Deposited: 06 Feb 2012 19:25
Last Modified: 10 May 2012 15:12
URI: http://srodev.sussex.ac.uk/id/eprint/20540
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