Quality of life measures in head and neck cancer

Llewellyn, C D (2010) Quality of life measures in head and neck cancer. In: Preedy, Victor R and Watson, Ronald R (eds.) Handbook of disease burdens and quality of life measures. Springer . Springer, New York, NY, pp. 2809-2828. ISBN 9780387786667

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Quality of life (QOL) is an important patient reported outcome (PRO) in head and neck cancer (HNC) where survival rates remain at approximately 50% overall. HNC specific Health Related Quality of Life (HR-QOL) instruments typically measure aspects of communication, swallowing, chewing, nutrition and cosmesis. Nine disease specific HR-QOL instruments have been published for patients with HNC focusing on a range of treatments and outcomes. Treatment for HNC results in medium term morbidity and depression, much of which has been shown to improve within 1 year. There is no clear evidence for the impact of disease and treatment on PROs such as QOL. The emotional sequelae and perception of physical limitations may be more important to the patient than the actual limitations resulting from HNC and treatment. This chapter highlights the insensitivity of general measures of HR-QOL to accurately illustrate HNC specific problems or treatment related effects. The majority of published studies do not interpret HR-QOL scores in terms of clinical relevance. Using a global or total score for examining effects of treatment induced change may not be appropriate for this patient group. Further research is needed into the potentially modifiable aspects of QOL or modifiable factors related to PROs in order to design appropriate interventions.

Item Type: Book Section
Schools and Departments: Brighton and Sussex Medical School > Primary Care and Public Health
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0001 Medicine and the state. Including medical statistics, medical economics, provisions for medical care, medical sociology > RA0407 Health status indicators. Medical statistics and surveys
Depositing User: Jessica Stockdale
Date Deposited: 22 Nov 2010
Last Modified: 29 Nov 2017 17:38
URI: http://srodev.sussex.ac.uk/id/eprint/2544
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