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Susceptibility of a Field-Derived, Bacillus thuringiensis-Resistant Strain of Diamondback Moth to In Vitro-Activated Cry1Ac Toxin
journal contribution
posted on 2023-06-08, 08:12 authored by Ali H Sayyed, Roxani Gatsi, Thaleia Kouskoura, Denis J Wright, Neil CrickmoreNeil CrickmoreResistant and susceptible populations of the diamondback moth (Plutella xylostella) were tested with crystalline, solubilized, and partially and fully activated forms of the Bacillus thuringiensis Cry1Ac -endotoxin. Fully activated toxin greatly reduced the resistance ratio (ratio of the 50% lethal concentration for the resistant population to that for the susceptible population) of the resistant population, suggesting that a defect in toxin activation is a major resistance mechanism.
History
Publication status
- Published
Journal
Applied and Environmental MicrobiologyISSN
0099-2240External DOI
Issue
9Volume
67Page range
4372-4373Pages
2.0Department affiliated with
- Biochemistry Publications
Notes
NC directed this work, all material was prepared by Gatsi and Kouskoura at Sussex with insect bioassays being performed by collaborators in London. The work describes how the enzymatic modification of a toxin can partially overcome an insect's resistance to that toxinFull text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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