Parallel evolution of Bt toxin resistance in Lepidoptera

Crickmore, Neil, Badenes-Pérez, Francisco, Baxter, Simon, Heckel, David, Jiggins, Chris, Kain, Wendy, Morrison, Anna, Vogel, Heiko and Wang, Ping (2011) Parallel evolution of Bt toxin resistance in Lepidoptera. Genetics, 189 (2). pp. 675-679. ISSN 0016-6731

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Despite the prominent and worldwide use of Bt insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.

Item Type: Article
Additional Information: Part of a multi-institute project to be identify the mechanism of resistance of major pest insects to the Bacillus thuringiensis biological pesticide.
Schools and Departments: School of Life Sciences > Biochemistry
Subjects: Q Science
Depositing User: Neil Crickmore
Date Deposited: 06 Feb 2012 21:26
Last Modified: 26 Jun 2013 08:34
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