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Interferon Gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum
journal contribution
posted on 2023-06-08, 10:11 authored by R C Pollok, M J Farthing, M Bajaj-Elliot, I R Sanderson, V McDonaldNo description supplied
History
Publication status
- Published
Journal
GastroenterologyISSN
0016-5085External DOI
Issue
1Volume
120Page range
99-107Department affiliated with
- Clinical and Experimental Medicine Publications
Notes
This study demonstrates the role of IFNy in enterocyte resistance to C.parvum infection acting through JAK/STAT signalling and alteration of intracellular Fe. This may explain in part the variable susceptibility to infection in humans. Pollok was my PhD student. I was involved in all stages of the study.Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-07Usage metrics
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