Obtaining snapshots of genetic variation using hemiclonal analysis

Abbott, Jessica K and Morrow, Edward H (2011) Obtaining snapshots of genetic variation using hemiclonal analysis. Trends in Ecology & Evolution, 26 (7). pp. 359-368. ISSN 0169-5347

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Hemiclones are naturally occurring or artificially produced individuals that share a single specific genetic haplotype. Natural hemiclones are produced via hybridization between two closely related species, whereas hemiclonal analysis in Drosophila is carried out in the laboratory via crosses with artificially created ‘clone-generator’ females with a specific genetic make-up. Hemiclonal analysis in Drosophila has been applied successfully to date to obtain measures of standing genetic variation for numerous traits. Here, we review the current hemiclonal literature and suggest future directions for hemiclonal research, including its application in molecular and genomic studies, and the adaptation of natural hemiclonal systems to carry out Drosophila-type studies of standing genetic variation.

Item Type: Article
Schools and Departments: School of Life Sciences > Evolution, Behaviour and Environment
Subjects: Q Science > QH Natural history > QH0301 Biology > QH0359 Evolution
Depositing User: Ted Morrow
Date Deposited: 02 Aug 2012 11:07
Last Modified: 06 Feb 2013 14:43
URI: http://srodev.sussex.ac.uk/id/eprint/40281
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