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How flow cytometry is changing the study of TB immunology and clinical diagnosis

journal contribution
posted on 2023-06-08, 12:40 authored by S Fuhrmann, M Streitz, Florian KernFlorian Kern
The application of flow cytometry has hugely advanced the field of tuberculosis (TB) across all areas of research ranging from diagnostic tests to understanding the underlying immunology. As cellular responses are understood to be the mainstay of the immune response in the control of TB it is very likely that polychromatic flow will become the tool of choice for assessing the effects of vaccination. Results are particularly encouraging in this area. The development of a new type of diagnostic test, a prototype of which has been reported, may be the spin-off of a broad and systematic approach to understanding and profiling the T-cell response to TB. It is obvious that flow cytometry will not be able to address all research questions in the field of TB. However, its enormous flexibility as a technology will make it the tool of choice in many situations. An ever increasing availability of flow cytometers, even in resource-poor countries, will rapidly change the face of TB research and management in the years ahead.

History

Publication status

  • Published

Journal

Cytometry. Part A

ISSN

1552-4922

Publisher

Wiley-Blackwell

Issue

11

Volume

73

Page range

1100-1106

Department affiliated with

  • Clinical and Experimental Medicine Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-10-26

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