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Changes in anti-heat shock protein 27 antibody and C-reactive protein levels following cardiac surgery and their association with cardiac function in patients with cardiovascular disease

journal contribution
posted on 2023-06-08, 13:45 authored by Amir Ali Rahsepar, Asadollah Mirzaee, Fatemeh Moodi, Mohsen Moohebati, Shima Tavallaie, Fatemeh Khorashadizadeh, Ali Eshraghi, Maryam-Sadat Alavi, Laya Zarrabi, Mostafa Sajjadian, Maral Amini, Roshanak Khojasteh, Roghayeh Paydar, Somayeh Mousavi, Majid Ghayour-Mobarhan, Gordon FernsGordon Ferns
The relationship between serum anti-heat shock protein (Hsp)27 antibody and high sensitive C-reactive protein (hs-CRP) levels and indices of cardiac function were investigated in patients undergoing coronary artery bypass grafting (CABG) or heart valve replacement. The changes in anti-Hsp27 antibody titers and hs-CRP levels were compared among patients undergoing off-pump and on-pump CABG or valvular heart replacement. Fifty-three patients underwent off-pump, on-pump CABG, and heart valvular replacement in each group. Serum anti-Hsp27 titers and hs-CRP values were measured 24 h before and after the operation and at discharge. Echocardiography was performed before surgery and before discharge. The results were compared with values from 83 healthy controls. hs-CRP levels increased and anti-Hsp27 antibody decreased following surgery (P?

History

Publication status

  • Published

Journal

Cell Stress and Chaperones

ISSN

1355-8145

Publisher

Springer

Volume

18

Page range

65-74

Department affiliated with

  • Division of Medical Education Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-11-16

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