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Changes in small dense low-density lipoprotein levels following acute coronary syndrome
journal contribution
posted on 2023-06-08, 13:46 authored by Mahdi Reza Emadzadeh, Maryam-Sadat Alavi, Mohammad Soukhtanloo, Toktam Mohammadpour, Amir Ali Rahsepar, Shima Tavallaie, Roshanak Khojasteh, Roghayeh Paydar, Maral Amini, Seyyed Mohammad Reza Parizadeh, Saeed Akhlaghi, Majid Ghayour-Mobarhan, Gordon FernsGordon FernsLow-density lipoprotein (LDL), especially small dense LDL (sdLDL), plays a role in atherogenesis. We compared baseline sdLDL levels between healthy controls and patients with acute coronary syndrome (ACS). Blood samples were taken from patients diagnosed with myocardial infarction ([MI] n = 104) and unstable angina ([UA] n = 100). Both sdLDL and high-sensitivity C-reactive protein (hsCRP) levels were determined on admission and in the next 24 hours after the onset of symptoms. Baseline concentration of sdLDL was significantly higher in patients presenting with ACS than controls (P < .05). In the 24 hours following ACS, the sdLDL levels decreased insignificantly in both groups of patients with ACS (P > .05). The changes in sdLDL values were not significantly different between MI and UA participants (P > .05). Patients with ACS have higher concentration of sdLDL compared with the controls.
History
Publication status
- Published
Journal
AngiologyISSN
1940-1574Publisher
SageExternal DOI
Issue
3Volume
64Page range
216-222Department affiliated with
- Division of Medical Education Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-11-16Usage metrics
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