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Modelling and simulation of cell migration in heterogeneous media

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conference contribution
posted on 2023-06-08, 15:20 authored by Charles Martin Elliott, Bjorn Stinner, Vanessa StylesVanessa Styles, Chandrasekhar VenkataramanChandrasekhar Venkataraman
Cell motility is a complex process comprising, among others, cytoskeletal remodelling and growth, active force generation, chemical transport and reaction of multiple substances inside and outside the cell as well as on the cell membrane, anisotropic material behavior of the cell and of the extracellular matrix (ECM), and proteolytic cleavage of the ECM. We are working on an evolving finite element based computational framework that is able to incorporate models and methods for all the key features of cell motility. The approach exploits a mesoscopic point of view and aims at a comprehensive 3D model allowing for the simulation of cell motility at reasonable computational costs. In the presentation we will first sketch the overall framework, addressing all the respective models and methods, and will then focus on some essential subunits.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

CMBE15: 4th International Conference on Computational & Mathematical Biomedical Engineering, 29th June - 1st July 2015 École Normale Supéerieure de Cachan, Cachan (Paris) France

Publisher

CMBE

Page range

401-404

Pages

867.0

Event name

4th International Conference Computational & Mathematical Biomedical Engineering

Event location

Paris, France

Event type

conference

Event date

29 June - 01 July, 2015

Book title

CMBE15: 4th International Conference on Computational & Mathematical Biomedical Engineering, 29th June - 1st July 2015 École Normale Supéerieure de Cachan, Cachan (Paris) France

Place of publication

Swansea, UK

ISBN

9780956291431

Department affiliated with

  • Mathematics Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Editors

Perumal Nithiarasu, Elisa Budyn

Legacy Posted Date

2015-11-24

First Open Access (FOA) Date

2015-11-24

First Compliant Deposit (FCD) Date

2015-11-24

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