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A fluorescence lifetime extraction algorithm based on multiple signal classification

journal contribution
posted on 2023-06-08, 19:11 authored by Hongqi Yu, David Day-Uei Li
The multiple signal classification algorithm has been widely used in array signal processing for direction-of-arrival estimations. In this paper, we applied this algorithm to estimate fluorescence lifetimes for fluorescence lifetime imaging microscopy (FLIM) for the first time to our knowledge. Monte Carlo simulations were carried out to test its performances in comparison with the previously reported integral equation method, center-of-mass method and phasor method. Simulation results show that the proposed algorithm can achieve comparable or better results than the others. More importantly, it can easily resolve multi-exponential decays.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Electronics Letters

ISSN

0013-5194

Publisher

Institution of Engineering and Technology

Issue

1

Volume

51

Page range

81-83

Department affiliated with

  • Engineering and Design Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2014-12-02

First Compliant Deposit (FCD) Date

2014-12-02

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