Li, David Day-Uei, Yu, Hongqi and Chen, Yu (2015) Fast bi-exponential fluorescence lifetime imaging analysis methods. Optics Letters, 40 (3). pp. 336-339. ISSN 0146-9592
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Abstract
A new hardware-friendly bi-exponential fluorescence lifetime imaging (FLIM) algorithm has been proposed. Compared to conventional FLIM software, the proposed algorithms are non-iterative offering direct calculation of lifetimes and therefore suitable for real-time applications. They can be applicable to single-channel or 2D multi-channel time-correlated single-photon counting (TCSPC) systems. The proposed methods have been tested on both synthesized and realistic FLIM data, and we have compared their performances with other recently proposed non-fitting bi-exponential techniques showing promising applications in future massive solid-state TCSPC imagers.
Item Type: | Article |
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Keywords: | Fluorescence lifetime imaging microscopy, photon counting, time-resolved fluorescence imaging |
Schools and Departments: | School of Engineering and Informatics > Engineering and Design |
Subjects: | Q Science > QA Mathematics > QA0273 Probabilities. Mathematical statistics Q Science > QA Mathematics > QA0075 Electronic computers. Computer science Q Science > QC Physics > QC0350 Optics. Light > QC0450 Spectroscopy T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK0452 Electric apparatus and materials. Electric circuits. Electric networks |
Depositing User: | David Day-Uei Li |
Date Deposited: | 03 Dec 2014 09:04 |
Last Modified: | 08 Mar 2017 08:23 |
URI: | http://srodev.sussex.ac.uk/id/eprint/51569 |
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