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The effect of storage conditions on the physical stability of tablets
journal contribution
posted on 2023-06-08, 19:18 authored by Ali Nokhodchi, Yousef JavadzadehThis article reviews the effect of moisture on the postcompaction properties of pharmaceutical solid dosage forms. It was stated that the amount of moisture adsorbed by drugs or excipients influences hardness, disintegration time of compacts and the dissolution rate of drugs. These changes may alter bioavailability and therapeutic efficacy, even though the drug potency and purity appear unaltered.
History
Publication status
- Published
Journal
Pharmaceutical Technology EuropeISSN
1753-7967Publisher
Advanstar Communications (UK) Ltd.Issue
1Volume
19Page range
20-26Department affiliated with
- Chemistry Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2015-01-07Usage metrics
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