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The effect of storage conditions on the physical stability of tablets

journal contribution
posted on 2023-06-08, 19:18 authored by Ali Nokhodchi, Yousef Javadzadeh
This article reviews the effect of moisture on the postcompaction properties of pharmaceutical solid dosage forms. It was stated that the amount of moisture adsorbed by drugs or excipients influences hardness, disintegration time of compacts and the dissolution rate of drugs. These changes may alter bioavailability and therapeutic efficacy, even though the drug potency and purity appear unaltered.

History

Publication status

  • Published

Journal

Pharmaceutical Technology Europe

ISSN

1753-7967

Publisher

Advanstar Communications (UK) Ltd.

Issue

1

Volume

19

Page range

20-26

Department affiliated with

  • Chemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-01-07

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