Sandham, David A, Aldcroft, Clive, Baettig, Urs, Barker, Lucy, Beer, David, Bhalay, Gurdip, Brown, Zarin, Dubois, Gerald, Budd, David, Bidlake, Louise, Campbell, Emma, Cox, Brian, Everatt, Brian, Harrison, David, Leblanc, Catherine J, Manini, Jodie, Profit, Rachael, Stringer, Rowan, Thompson, Katy S, Turner, Katharine L, Tweed, Morris F, Walker, Christopher, Watson, Simon J, Whitebread, Steven, Willis, Jennifer, Williams, Gareth and Wilson, Caroline (2007) 2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists. Bioorganic and Medicinal Chemistry Letters, 17 (15). pp. 4347-4350. ISSN 0960-894X
Full text not available from this repository.Abstract
High throughput screening identified a phenoxyacetic acid scaffold as a novel CRTh2 receptor antagonist chemotype, which could be optimised to furnish a compound with functional potency for inhibition of human eosinophil shape change and oral bioavailability in the rat.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Chemistry |
Subjects: | Q Science > QD Chemistry |
Depositing User: | Tom Gittoes |
Date Deposited: | 13 Jan 2015 07:44 |
Last Modified: | 13 Jan 2015 07:44 |
URI: | http://srodev.sussex.ac.uk/id/eprint/52055 |