Synthesis and epimerisation studies on carbohydrate derived bicyclic tetronate esters: the synthesis of furanofurans related to the cytotoxic metabolite goniofufurone

Cagnolini, Cristiano, Ferri, Marina, Jones, Peter R, Murphy, Patrick J, Ayres, Barry and Cox, Brian (1997) Synthesis and epimerisation studies on carbohydrate derived bicyclic tetronate esters: the synthesis of furanofurans related to the cytotoxic metabolite goniofufurone. Tetrahedron, 53 (13). pp. 4815-4820. ISSN 0040-4020

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Abstract

The synthesis of the D-xylo- 12, D-lyxo- 13, D-ribo- 14 and D-arabino-furanofurans15 was accomplished from the readily available butyrolactones 4 and 5via a non-classical Wittig cyclisation/hydrogenation sequence; these compounds are analogues of the cytotoxic natural product goniofufurone.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
Subjects: Q Science > QD Chemistry
Depositing User: Tom Gittoes
Date Deposited: 13 Jan 2015 15:05
Last Modified: 13 Jan 2015 15:05
URI: http://srodev.sussex.ac.uk/id/eprint/52098
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