Booth, D A (1972) Modulation of the feeding response to peripheral insulin, 2-deoxyglucose or 3-0-methyl glucose injection. Physiology and Behavior, 8 (6). pp. 1069-1076. ISSN 0031-9384
Full text not available from this repository.Abstract
The effects of circadian rhythm, delayed access to food, bilateral subdiaphragmatic vagotomy and bilateral adrenal medullectomy were examined. Like normal insulin injected subcutaneously, 2-deoxy-D-glucose injected intraperitoneally induces feeding in sated rats by night as well as by day. The unmetabolized glucose analogue 3-O-methyl-D-glucopyranose detectably increases feeding by day. On delayed return of food after 2-deoxyglucose injection into mildly deprived rats, feeding is at first inhibited and then facilitated. Vagotomy but not medullectomy interferes with 2-deoxyglucose-induced feeding, whereas medullectomy but not vagotomy interferes with insulin-induced feeding, when dosages near the optima for intact rats are used. However, when low doses are given, neither surgically induced deficit is evident.
Item Type: | Article |
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Schools and Departments: | School of Psychology > Psychology |
Subjects: | Q Science > QP Physiology > QP0501 Animal biochemistry Q Science > QZ Psychology |
Depositing User: | prof. David Booth |
Date Deposited: | 01 Mar 2015 11:14 |
Last Modified: | 24 Apr 2015 14:32 |
URI: | http://srodev.sussex.ac.uk/id/eprint/53122 |
Project Name | Sussex Project Number | Funder | Funder Ref |
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Unset | Unset | MRC-MEDICAL RESEARCH COUNCIL | Unset |