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The association between conduct problems and the initiation and progression of marijuana use during adolescence: a genetic analysis across time
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posted on 2023-06-08, 21:45 authored by Katherine Shelton, Kate Lifford, Tom Fowler, Frances Rice, Mike Neale, Gordon Harold, Anita Thapar, Marianne van den BreeThe present study used a prospective, longitudinal design to investigate genetic and environmental influences on the association between earlier conduct problems and the initiation and progression of marijuana use during adolescence. Parent- and teacher-reported conduct problems assessed at Time 1 (1996) and self-reported marijuana use assessed at Time 2 (2004) were available for 1088 adolescent twin pairs participating in the Cardiff Study of All Wales and North West of England Twins (CaStANET). Using a novel approach to the modeling of initiation and progression dimensions in substance use, findings suggested that the initiation of marijuana use in adolescence was influenced by genetic, common and unique environmental factors. The progression (or frequency) of marijuana use was influenced by genetic and unique environmental factors. Findings for conduct problems indicated that while the presence or absence of conduct problems was largely heritable, the relative severity of conduct problems appeared to be more strongly environmentally influenced. Multivariate model fitting indicated that conduct problems in childhood and early adolescence made a small but significant contribution to the risk for marijuana use 8 years later. © 2006 Springer Science+Business Media, LLC.
History
Publication status
- Published
Journal
Behavior GeneticsISSN
0001-8244Publisher
Springer New YorkExternal DOI
Issue
2Volume
37Page range
314-325Department affiliated with
- Psychology Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2015-08-11Usage metrics
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