University of Sussex
Browse

File(s) under permanent embargo

Emotional memory for words- separating content and context

journal contribution
posted on 2023-06-08, 22:10 authored by Nicholas Medford, Mary L Phillips, Barbara Brierley, Michael Brammer, Edward T Bullmore, Aanthony S David
It is now well established that emotion enhances episodic memory. However, it remains unclear whether the same neural processes underlie enhancement of memory for both emotional stimuli and neutral stimuli encoded in an emotive context. We designed an experiment that specifically attempted to separate these effects and that was validated on 30 participants. We then used functional magnetic resonance imaging (fMRI) to examine the neural correlates of encoding and retrieval of the two classes of stimuli in 12 healthy male volunteers. We predicted that aversive emotional context would enhance memory regardless of content and that activation of anterior cingulate would be inversely related to retrieval of aversive items. Both predictions were supported. Furthermore we demonstrated apparent asymmetrical lateralisation of activation in the hippocampal/parahippocampal complex during recognition of words from aversive sentences: more left-sided activation for neutral words from aversive contexts, and more right-sided activation for aversive content words. These findings, if applicable to the wider population, may have application in a range of psychiatric disorders

History

Publication status

  • Published

File Version

  • Published version

Journal

Psychiatry Research: Neuroimaging

ISSN

0925-4927

Publisher

Elsevier

Issue

3

Volume

138

Page range

247-258

Department affiliated with

  • BSMS Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-08-20

First Compliant Deposit (FCD) Date

2015-08-20

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC