Factors influencing feeding elicited by intracranial noradrenaline in rats

Matthews, J W, Booth, D A and Stolerman, I P (1978) Factors influencing feeding elicited by intracranial noradrenaline in rats. Brain Research, 141 (1). pp. 119-128. ISSN 0006-8993

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An improved design of microcannula was used to inject noradrenaline into discrete areas of the rat hypothalamus. The area of the paraventricular nucleus was shown to be a more effective site than the midlateral anterior hypothalamus for eliciting feeding with noradrenaline (4.8 μg). The magnitude but not the direction of the effect of noradrenaline on feeding was influenced by the day-night cycle. The facilitating effect of the drug reached significance in the light period but not in the dark period, possibly because the baseline food intake was higher by night than by day. The facilitation of feeding occurred whether the rats were maintained and tested on a diet of solid or liquid food.

Item Type: Article
Schools and Departments: School of Psychology > Psychology
Subjects: B Philosophy. Psychology. Religion > BF Psychology > BF0180 Experimental psychology
Q Science > QP Physiology > QP0001 General Including influence of the environment > QP0136 Appetite
Q Science > QP Physiology > QP0501 Animal biochemistry > QP0901 Experimental pharmacology
R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
Depositing User: prof. David Booth
Date Deposited: 28 Aug 2015 12:48
Last Modified: 28 Aug 2015 12:48
URI: http://srodev.sussex.ac.uk/id/eprint/56350
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