Broad, R and Leigh, P N (2015) Recognising facial onset sensory motor neuronopathy syndrome: insight from six new cases. Practical Neurology, 15 (4). pp. 293-297. ISSN 1474-7758
Full text not available from this repository.Abstract
Facial onset sensory and motor neuronopathy (FOSMN) was first described in 2006 as an apparently sporadic neurodegenerative disease. Thirty cases have been reported to date. We summarise six new cases, highlighting the key clinical aspects of FOSMN and how to differentiate it from motor neurone disease (amyotrophic lateral sclerosis). Typically, patients present with slowly evolving numbness of the face followed by bulbar and proximal (neck and arm) weakness. However, one of our patients presented with a motor syndrome and his abnormal blink reflex studies provided a useful diagnostic clue. This extends the spectrum of the syndrome and emphasises that FOSMN should be considered in the differential diagnosis of motor neurone disease. We discuss the pathophysiology, diagnosis, prognosis and management considerations of FOSMN.
Item Type: | Article |
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Schools and Departments: | Brighton and Sussex Medical School > Neuroscience |
Subjects: | R Medicine R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry > RC0346 Neurology. Diseases of the nervous system Including speech disorders |
Depositing User: | Patricia Butler |
Date Deposited: | 16 Sep 2015 07:47 |
Last Modified: | 25 Jul 2017 15:07 |
URI: | http://srodev.sussex.ac.uk/id/eprint/56775 |