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Memories are made of this: synergy of T cell receptor and cytokine signals in CD4(+) central memory cell survival

journal contribution
posted on 2023-06-08, 22:36 authored by Stefano Caserta, Rose Zamoyska
The ability of the immune system to 'remember' a previous encounter with antigen is the hallmark of the adaptive immune response. The signals required for CD4(+) memory T cell survival are not well understood, and a recent paper lends new biochemical insights into how memory T cells might optimally be preserved through the convergence of signals from the engagement of cytokine and antigen-specific T cell receptors.

History

Publication status

  • Published

Journal

Trends in Immunology

ISSN

1471-4906

Publisher

Elsevier

Issue

6

Volume

28

Page range

245-248

Department affiliated with

  • Clinical and Experimental Medicine Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-09-30

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