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Intersex related gene expression profiles in clams Scrobicularia plana: molecular markers and environmental application

journal contribution
posted on 2023-06-08, 23:08 authored by Corina M Ciocan, Elena Cubero-Leon, William J Langston, Nick Pope, Keith Cornelius, E M Hill, Diana Alvarez-Munoz, Paolo Indiveri, Adelaide Lerebours, Christophe Minier, Jeanette M Rotchell
Intersex, the appearance of female characteristics in male gonads, has been identified in several aquatic species. It is a widespread phenomenon in populations of the bivalve, Scrobicularia plana, from the southwest coast of the U.K. Genes previously identified as differentially expressed (ferritin, testicular haploid expressed gene, THEG, proliferating cell nuclear antigen, PCNA; receptor activated protein kinase C, RACK; cytochrome B, CYB; and cytochrome c oxidase 1, COX1) in intersex clams relative to normal male clams, were selected for characterisation and an environmental survey of the Channel region. Transcripts were significantly differentially expressed at sites with varying intersex incidence and contaminant burdens. Significant correlations between specific gene expressions, key contaminants and sampling locations have been identified, though no single gene was associated with intersex incidence. The results highlight the difficulty in understanding the intersex phenomenon in molluscs where there is still a lack of knowledge on the control of normal reproduction.

History

Publication status

  • Published

Journal

Marine Pollution Bulletin

ISSN

0025-326X

Publisher

Elsevier

Issue

2

Volume

95

Page range

610-617

Department affiliated with

  • Evolution, Behaviour and Environment Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-11-11

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