Intentional and non-intentional non-adherence to medication amongst breast cancer patients

Atkins, L. and Fallowfield, L. J. (2006) Intentional and non-intentional non-adherence to medication amongst breast cancer patients. European Journal of Cancer, 42 (14). pp. 2271-6. ISSN 0959-8049

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This study aimed to investigate the prevalence of and factors associated with non-adherence to medication amongst a sample of breast cancer patients. 131 women with stable disease were interviewed and completed standardised psychological measures. 55% of women reported non-adherence to medication frequently or occasionally, with younger women and those who disliked taking their medication being significantly less adherent (P = 0.015, P = 0.001). Women who deliberately omitted taking their tablets occasionally or frequently had significantly lower scores, indicative of a weaker influence, on 'internal' and 'powerful others' dimensions of health locus of control (P = 0.032, P = 0.009). Despite a life-threatening diagnosis, patients may not adhere to medication representing a potential missed opportunity for health gain and waste of resources. Furthermore, interpretation of clinical trial data may be misleading without adherence information. More research is needed to identify those at risk for non-adherence. If other routes of administration are available these options should be discussed with patients to maximise efficacy of therapy.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Sussex Health Outcomes Research & Education in Cancer (SHORE-C)
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology Including cancer and carcinogens
B Philosophy. Psychology. Religion > BF Psychology
Depositing User: Lesley Fallowfield
Date Deposited: 28 Nov 2006
Last Modified: 06 Sep 2017 18:32
Google Scholar:77 Citations

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