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Matrix-assisted diffusion-ordered spectroscopy
journal contribution
posted on 2023-06-09, 01:15 authored by R Evans, Iain DayDiffusion NMR is a potentially routine tool in the analysis of mixtures, from industrial and synthetic outputs to natural products. However, the technique struggles to resolve species of similar size. Matrix-assisted DOSY offers a flexible approach to resolving such ambiguities on the basis of the chemical structures involved and on their interactions with a larger co-solute or matrix. The use of chromatographic supports, surfactants and polymers, in particular, is illustrated. The resolution of a wide range of different analyte mixtures, on the basis of differences in chemical structure and in stereochemistry, is demonstrated.
Funding
NMR Studies of the Early Stages of Aggregation Phenomena; G0186; EPSRC-ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL; EP/H025367/1
History
Publication status
- Published
File Version
- Accepted version
Journal
RSC AdvancesISSN
2046-2069Publisher
Royal Society of ChemistryExternal DOI
Issue
52Volume
6Page range
47010-47022Department affiliated with
- Chemistry Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2016-05-16First Open Access (FOA) Date
2017-04-26First Compliant Deposit (FCD) Date
2016-05-16Usage metrics
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