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A conserved trans-regulatory landscape for scute expression on the notum of cyclorraphous Diptera

journal contribution
posted on 2023-06-09, 02:17 authored by Joanna Richardson, Pat Simpson
Bristles on the notum of many cyclorraphous flies are arranged into species-specific stereotyped patterns. The positions of bristles correlate with differences in the spatial expression of the scute (sc) gene in those species examined so far. However, a major upstream activator of scute, Pannier (Pnr), is expressed in a conserved domain over the entire medial notum. Here we examine the expression patterns in Calliphora vicina of stripe (sr), u-shaped (ush), caupolican (caup) and wingless (wg), genes known to modify the activity of Pnr or to act downstream of Pnr in Drosophila. We find that, with minor differences, their expression patterns are conserved. This suggests that the function of a trans-regulatory network of genes is relatively unchanged in derived Diptera and that many differences are likely to be due to changes in cis-regulatory sequences of scute.

History

Publication status

  • Published

File Version

  • Published version

Journal

Development Genes and Evolution

ISSN

0949-944X

Publisher

Springer Verlag

Issue

1

Volume

216

Page range

29-38

Department affiliated with

  • Biochemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2016-07-28

First Compliant Deposit (FCD) Date

2016-07-27

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