O'Bryan, Matt and Paudyal, Priyamvada (2016) [Abstract] Cross-shift lung function in relation to cotton dust and endotoxin exposure in non-smoking female textile workers: a cross-sectional study. European Respiratory Journal, 48 (S60). ISSN 0903-1936

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Abstract

Background: Exposure to inhalable cotton dust particulates and endotoxin have been previously associated with respiratory symptoms and acute changes in lung function.

Objectives: This study investigates the cross-shift decline in lung function of female non-smoking textile workers in relation to dust and endotoxin exposure.

Methods: We present the subgroup analysis of a previously published study in Nepalese textile workers. 295 workers in four textile sectors (garment, carpet, weaving and recycling) completed a respiratory health questionnaire. A subset of 127 workers performed cross-shift spirometry. Personal exposure to inhalable dust and endotoxin was measured for 32 workers; remaining workers were assigned the geometric mean values of all workers within the same textile sector. Multiple regression analysis were carried out to identify independent predictors of cross-shift decline in lung function.

Results: The overall prevalence of persistent cough, persistent phlegm, chest tightness-, wheeze- and breathlessness-ever was 9.2%, 6.1%, 3.1%, 8.5% and 13.9% respectively. A significant cross-shift reduction (p<0.001) in forced expiratory volume in 1s (FEV1) and forced vital capacity (FVC) were measured. Dust and endotoxin exposure did not significantly predict the cross-shift decline in lung function.

Conclusions: The cross-shift decline in lung function supports the implementation of measures to improve the working environment in textile sectors. A well-designed study addressing occupational exposures along with the exposures to concomitant domestic and environmental pollutants will help to better understand the respiratory health of textile workers.

Item Type:	Article
Schools and Departments:	Brighton and Sussex Medical School > Primary Care and Public Health Brighton and Sussex Medical School > Division of Medical Education
Depositing User:	Priyamvada Paudyal
Date Deposited:	23 Nov 2016 17:29
Last Modified:	25 Sep 2017 09:49
URI:	http://srodev.sussex.ac.uk/id/eprint/65624

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