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A practical approach to the pharmacological management of hypertension in older people

journal contribution
posted on 2023-06-09, 04:43 authored by Nikesh Parekh, Amy Page, Khalid Mustafa AliKhalid Mustafa Ali, Kevin DaviesKevin Davies, Chakravarthi RajkumarChakravarthi Rajkumar
Hypertension is the leading cause of cardiovascular (CV) morbidity and mortality in adults over the age of 65. The first part of this paper is an overview, summarizing the current guidelines on the pharmacological management of hypertension in older adults in Europe and the USA, and evidence from key trials that contributed to the guidelines. In the second part of the paper, we will discuss the major challenges of managing hypertension in the context of multimorbidity, including frailty, orthostatic hypotension (OH), falls and cognitive impairment that are associated with ageing. A novel ‘BEGIN’ algorithm is proposed for use by prescribers prior to initiating antihypertensive therapy to guide safe medication use in older adults. Practical suggestions are highlighted to aid practitioners in making rational decisions to treat and monitor hypertension, and for considering withdrawal of antihypertensive drugs in the complex older person.

History

Publication status

  • Published

File Version

  • Published version

Journal

Therapeutic Advances in Drug Safety

ISSN

2042-0986

Publisher

SAGE Publications

Issue

4

Volume

8

Page range

117-132

Department affiliated with

  • BSMS Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2017-01-13

First Compliant Deposit (FCD) Date

2017-01-13

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