CIRCRES_2016_309982_R1_20161008.pdf (571.33 kB)
Cytomegalovirus as a driver of excess cardiovascular mortality in rheumatoid arthritis: a red herring or a smoking gun?
journal contribution
posted on 2023-06-09, 04:47 authored by Alejandra Pera RojasAlejandra Pera Rojas, Iain Broadley, Kevin DaviesKevin Davies, Florian KernFlorian KernRheumatoid arthritis (RA) is the most common inflammatory arthritis worldwide. Apart from its well known manifestations involving the joints (e.g. deformity, swelling, synovial inflammation), there are widespread, extra-articular manifestations that also involve the cardiovascular (CV) system. The consequences of CV involvement are often serious; cerebrovascular disease, ischemic heart disease and CV disease (CVD)-associated death are up to 50% higher in the context of RA leading to a reduction of life-expectancy in these patients of 3-10 years compared with the general population. To date, no satisfactory explanation of this phenomenon has been found, or maybe, it has been overlooked?
History
Publication status
- Published
File Version
- Accepted version
Journal
Circulation ResearchISSN
0009-7330Publisher
Lippincott, Williams & WilkinsExternal DOI
Issue
2Volume
120Page range
274-277Department affiliated with
- Clinical and Experimental Medicine Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2017-01-18First Open Access (FOA) Date
2017-07-20First Compliant Deposit (FCD) Date
2017-01-18Usage metrics
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