Mu et al 2012.pdf (3.95 MB)
Optic glomeruli and their inputs in Drosophila share an organizational ground pattern with the antennal lobes
journal contribution
posted on 2023-06-09, 04:59 authored by Laiyong Mu, Kei Ito, Jonathan Bacon, Nicholas J StrausfeldStudying the insect visual system provides important data on the basic neural mechanisms underlying visual processing. As in vertebrates, the first step in visual processing in insects is through a series of retinotopic neurons. Recent studies on flies have found that these converge onto assemblies of columnar neurons in the lobula, the axons of which segregate to project to discrete optic glomeruli in the lateral protocerebrum. This arrangement is much like the fly's olfactory system, in which afferents target uniquely identifiable olfactory glomeruli. Here, whole-cell patch recordings show that even though visual primitives are unreliably encoded by single lobula output neurons because of high synaptic noise, they are reliably encoded by the ensemble of outputs. At a glomerulus, local interneurons reliably code visual primitives, as do projection neurons conveying information centrally from the glomerulus. These observations demonstrate that in Drosophila, as in other dipterans, optic glomeruli are involved in further reconstructing the fly's visual world. Optic glomeruli and antennal lobe glomeruli share the same ancestral anatomical and functional ground pattern, enabling reliable responses to be extracted from converging sensory inputs.
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Publication status
- Published
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- Published version
Journal
Journal of NeuroscienceISSN
0270-6474Publisher
Society for NeuroscienceExternal DOI
Issue
18Volume
32Page range
6061-6071Department affiliated with
- Biology and Environmental Science Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2017-01-31First Open Access (FOA) Date
2017-01-31First Compliant Deposit (FCD) Date
2017-01-31Usage metrics
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