Incidence, prevalence and mortality rates of malaria in Ethiopia from 1990 to 2015: analysis of the global burden of diseases 2015

Deribew, Amare, Dejene, Tariku, Biruck, Kebede, Assefa Tessema, Gizachew, Adama Melaku, Yohannes, Misganaw, Awoke, Gebre, Teshome, Hailu, Asrat, Biadgilign, Sibhatu, Amberbir, Alemayehu, Desalegn Yirsaw, Biruck, Alemu Abajobir, Amanuel, Shafi, Oumer, F. Abera, Semaw, Negussu, Nebiyu, Mengistu, Belete, T. Amare, Azmeraw, Mulugeta, Abate, Mengistu, Birhan, Tadesse, Zerihun, Sileshi, Mesfin, Cromwell, Elizabeth, D. Glenn, Scott, Deribe, Kebede and Stanaway, Jeffrey (2017) Incidence, prevalence and mortality rates of malaria in Ethiopia from 1990 to 2015: analysis of the global burden of diseases 2015. Malaria Journal, 16. a271. ISSN 1475-2875

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Background: In Ethiopia there is no complete registration system to measure disease burden and risk factors accurately. In this study, the 2015 Global Burden of Diseases, Injuries and Risk factors (GBD) data were used to analyse the incidence, prevalence and mortality rates of malaria in Ethiopia over the last 25 years.

Methods: GBD 2015 used verbal autopsy (VA) surveys, reports, and published scientific articles to estimate the burden of malaria in Ethiopia. Age and gender-specific causes of death for malaria were estimated using Cause of Death Ensemble Modelling (CODEm).

Results: The number of new cases of malaria declined from 2.8 million (95% uncertainty interval (UI): 1.4-4.5million) in 1990 to 621,345 (95% UI: 462,230-797,442) in 2015. Malaria caused an estimated 30,323.9 deaths (95% UI: 11,533.3-61,215.3) in 1990 and 1,561.7 deaths (95% UI: 752.8-2,660.5) in 2015, a 94.8% reduction over the 25 years. Age-standardized mortality rate of malaria has declined by 96.5% between 1990 and 2015 with an annual rate of change (ARC) of 13.4%. Age-standardized malaria incidence rate among all ages and gender declined by 88.7% between 1990 and 2015. The number of disability-adjusted life years lost (DALY) due to malaria decreased from 2.2 million (95% UI: 0.76-4.7 million) in 1990 to 0.18 million (95% UI: 0.12-0.26 million) in 2015, with a total reduction 91.7%. Similarly, age-standardized DALY rate declined by 94.8% during the same period.

Conclusions: Ethiopia has achieved a 50% reduction target of malaria of the Millennium Development Goals (MDGs). The country should strengthen its malaria control and treatment strategies to achieve the Sustainable Development Goals (SDG).

Item Type: Article
Keywords: Malaria, millennium development goals, Ethipia, global burden of disease
Schools and Departments: Brighton and Sussex Medical School > Global Health and Infection
Research Centres and Groups: Wellcome Trust Brighton and Sussex Centre for Global Health Research
Depositing User: Esther Garibay
Date Deposited: 12 Jul 2017 12:25
Last Modified: 11 Sep 2017 10:32

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