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Gap junctional communication and development

journal contribution
posted on 2023-06-09, 07:25 authored by Sarah GuthrieSarah Guthrie, N Gilula
Embryonic development requires extensive interaction between cells; cell-to-cell communication through gap junctions may be one mechanism involved. Much correlative evidence suggests gap junctions are involved in cellular interactions during development. Recently, the biological role of junctions has been investigated using antibodies prepared against the major rat liver gap junction protein. Disrupting normal patterns of intercellular communication with such antibodies can drastically perturb development. Recent experiments emphasize, in particular, the importance of gap junctional communication for patterning processes.

History

Publication status

  • Published

Journal

Trends in Neurosciences

ISSN

0166-2236

Publisher

Elsevier

Issue

1

Volume

12

Page range

12-16

Department affiliated with

  • Neuroscience Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2017-07-26

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