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Optical force on diseased blood cells: towards the optical sorting of biological matter
journal contribution
posted on 2023-06-09, 07:33 authored by Juan Sebastian Totero Gongora, Andrea FratalocchiBy employing a series of massively parallel ab-initio simulations, we study how optical forces act on biological matter subject to morphological disease. As a representative case study, we here consider the case of Plasmodium falciparum on red blood cells (RBC) illuminated by a monochromatic plane wave. Realistic parameters for the geometry and the refractive index are then taken from published experiments. In our theoretical campaign, we study the dependence of the optical force on the disease stage for different incident wavelengths. We show that optical forces change significantly with the disease, with amplitude variation in the hundreds of pN range. Our results open up new avenues for the design of new optical systems for the treatment of human disease.
History
Publication status
- Published
File Version
- Published version
Journal
Optics and Lasers in EngineeringISSN
0143-8166Publisher
ElsevierExternal DOI
Volume
76Page range
40-44Department affiliated with
- Physics and Astronomy Publications
Research groups affiliated with
- Atomic, Molecular and Optical Physics Research Group Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2018-07-05First Compliant Deposit (FCD) Date
2018-07-04Usage metrics
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