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Khan, Raysa, Felix, Robert, Kemmitt, Paul D, Coles, Simon J, Tizzard, Graham J and Spencer, John (2018) N1-arylation of 1,4-benzodiazepine-2-ones with diaryliodonium salts. Synlett, 29 (02). pp. 193-198. ISSN 0936-5214
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Official URL: https://doi.org/10.1055/s-0036-1590920
Abstract
A library of N1-arylated 5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ones has been synthesized starting with unsymmetrical diaryliodonium salts using aqueous ammonia as a base. This can also be applied to a similar 1,3,4-benzotriazepin-2-one derivative.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Chemistry |
Subjects: | Q Science > QD Chemistry > QD0241 Organic chemistry |
Depositing User: | John Spencer |
Date Deposited: | 07 Sep 2017 09:15 |
Last Modified: | 16 Jan 2018 07:52 |
URI: | http://srodev.sussex.ac.uk/id/eprint/70020 |
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Project Name | Sussex Project Number | Funder | Funder Ref |
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A Precompetitive Modular Peptidomimetic Toolkit for Targeting PPIs iCASE | G1436 | EPSRC-ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL | EP/M507568/1 |