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Li, Alice H, Waddell, Simon J, Hinds, Jason, Malloff, Chad A, Bains, Manjeet, Hancock, Robert E, Lam, Wan L, Butcher, Philip D and Stokes, Richard W (2010) Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages. PLoS ONE, 5 (6). e11066. ISSN 1932-6203
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Official URL: http://www.plosone.org/article/info%3Adoi%2F10.137...
Abstract
Along with the recent identification of single nucleotide polymorphisms in H37Ra when compared to H37Rv, our demonstration of differential expression of PhoP-regulated and ESX-1 region-related genes during macrophage infection further highlights the significance of these genes in the attenuation of H37Ra.
Item Type: | Article |
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Schools and Departments: | Brighton and Sussex Medical School > Global Health and Infection |
Subjects: | Q Science > Q Science (General) Q Science > QR Microbiology > QR0075 Bacteria Q Science > QR Microbiology > QR0171 Microorganisms in the animal body |
Depositing User: | Simon Waddell |
Date Deposited: | 17 Jul 2012 14:15 |
Last Modified: | 22 Sep 2017 11:19 |
URI: | http://srodev.sussex.ac.uk/id/eprint/7639 |
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