The treatment of early breast cancer in women over the age of 70

Ring, A., Reed, M., Leonard, R., Kunkler, I., Muss, H., Wildiers, H., Fallowfield, L. J., Jones, A. and Coleman, R. (2011) The treatment of early breast cancer in women over the age of 70. British Journal of Cancer, 105. pp. 189-193. ISSN 1532-1827

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One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarises the existing evidence surrounding the management of early breast cancer in women aged 70 and over. The use of primary surgery and endocrine therapy, and adjuvant chemotherapy, radiotherapy, endocrine therapy and trastuzumab are discussed. Reference is made to ongoing clinical trials in this area and areas of controversy are highlighted.

Item Type: Article
Keywords: breast cancer; elderly; geriatric oncology
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Brighton and Sussex Medical School > Sussex Health Outcomes Research & Education in Cancer (SHORE-C)
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Depositing User: Jil Fairclough
Date Deposited: 30 Apr 2012 09:30
Last Modified: 29 Sep 2017 10:35
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