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The diagnostic, prognostic and therapeutic potential of circulating microRNAs in ovarian cancer.pdf (619.53 kB)

The diagnostic, prognostic and therapeutic potential of circulating microRNAs in ovarian cancer

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journal contribution
posted on 2023-06-09, 14:34 authored by Hamideh Aboutalebi, Afsane Bahrami, Atena Soleimani, Nikoo Saeedi, Farzad Rahmani, Majid Khazaei, Hamid Fiuji, Mojtaba Shafiee, Gordon FernsGordon Ferns, Amir Avan, Seyed Mahdi Hassanian
Ovarian cancer (OC) is often diagnosed at an advanced stage because of the late onset of symptoms, and this together with the lack of effective treatments, has meant it is associated with a very high mortality. The aberrant expression of MicroRNA (miRNA) contributes to the initiation and development of human tumors including OC. Several miRNAs are secreted by tumor cells and can be identified in body fluids. Serum miRNAs levels are associated with several clinical conditions, and may be used to predict prognosis and response to treatments in some cancers including OC. This review summarizes the current progresses regarding the potential applications of circulating miRNA as innovative biomarkers in OC.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

International Journal of Biochemistry and Cell Biology

ISSN

1357-2725

Publisher

Elsevier

Volume

124

Article number

a105765

Department affiliated with

  • BSMS Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2018-08-16

First Open Access (FOA) Date

2021-05-18

First Compliant Deposit (FCD) Date

2018-08-15

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