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Intron size and exon evolution in Drosophila

journal contribution
posted on 2023-06-09, 14:38 authored by Gabriel Marais, Pierre NouvelletPierre Nouvellet, Peter D Keightley, Brian Charlesworth
We have found a negative correlation between evolutionary rate at the protein level (as measured by d(N)) and intron size in Drosophila. Although such a relation is expected if introns reduce Hill-Robertson interference within genes, it seems more likely to be explained by the higher abundance of cis-regulatory elements in introns (especially first introns) in genes under strong selective constraints.

History

Publication status

  • Published

File Version

  • Published version

Journal

Genetics

ISSN

0016-6731

Publisher

Genetics Society of America

Issue

1

Volume

170

Page range

481-485

Department affiliated with

  • Evolution, Behaviour and Environment Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2018-08-17

First Compliant Deposit (FCD) Date

2018-08-16

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